Quick Fix time...
Well this "Print preview is blank and you cannot print pages from Internet Explorer" problem was evident on a clients machine, however I couldn't actually open the Page Setup page either to resolve it.
The solution I found was this very handy IEFix - General purpose fix for Internet Explorer utility and seems to do what it says on the tin. So nice one Ramesh Srinivasan and thank you!
I tried to run the ie-fix but unfortunately got the following message:-
Run-time error '-2147024770(8007007e)'
Automation error
The specified module could not be found
If anyone has any other suggestions they would be much appreciated!